Welcome to 4521 Mayfair St, tucked away on a quiet cul-de-sac in the heart of Bellaire and uniquely positioned with no through access giving an extra layer of privacy. This thoughtfully designed custom built home offers incredible flexibility with 4 beds, 4.5 baths, a private apartment (556 add'l sq ft with living space and kitchen), dedicated office, add'l flex space and spacious kitchen. One of the standout features is the presence of 2 spacious primary suites, both w/ oversized closets! You'll also find generous storage throughout, and even a convenient laundry chute from the upstairs primary closet along with notable features like double paned windows/doors and custom window treatments. Updates include: Roof (2024), HVAC (2024) and 2nd system mostly updated, Water heater (2024, 2025). Meticulously maintained, never flooded and ready to move in! Zoned to Horn Elementary & Bellaire High School and just minutes from parks, restaurants, the Texas Medical Center and Downtown.